What are biofilms in the context of chronic wounds?

Biofilms in the context of chronic wounds refer to clusters of bacteria that adhere to the wound surface. These biofilms are formed when bacteria aggregate and encase themselves in a protective layer of extracellular polymeric substances, which creates a complex community that is resistant to both the immune system and antibiotic treatment. This characteristic makes biofilms particularly challenging in managing chronic wounds, as they can lead to persistent inflammation and delay the healing process.

The presence of biofilms can hinder the normal healing processes by acting as a reservoir for infection and creating a hostile environment for tissue regeneration. Understanding the role of biofilms is crucial for healthcare providers when developing effective treatment strategies for chronic wounds, ensuring that interventions adequately target these bacterial communities.